Quick answer
"Laugh at" is an intransitive verb phrase which is often translated as "reírse de", and "about" is a preposition which is often translated as "sobre". Learn more about the difference between "laugh at" and "about" below.
laugh at
An intransitive verb phrase is a phrase that combines a verb with a preposition or other particle and does not require a direct object (e.g. Everybody please stand up.).
intransitive verb phrase
1. (general)
a. reírse de
My friends laughed at my new haircut.Mis amigos se rieron de mi nuevo corte de pelo.
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A preposition is a word that indicates the relationship between a noun and another word (e.g. He ran through the door.).
1. (concerning)
a. sobre
The movie we saw last night was about World War I.La película que vimos anoche era sobre la Primera Guerra Mundial.
b. acerca de
That new series about petroleum is fascinating.Esa nueva serie acerca del petróleo es fascinante.
c. de
I'm reading a book about history.Estoy leyendo un libro de historia.
d. por
My husband hasn't been feeling well lately. I'm worried about him.Mi esposo no se encuentra bien últimamente. Estoy preocupada por él.
2. (associated with)
a. en
There is something about his expression that intrigued me.Hay algo en su expresión que me intrigaba.
A word or phrase restricted in usage to literature or established writing (e.g. sex, once upon a time).
a. alrededor de
The girl put her arm about her teddy bear.La niña puso el brazo alrededor de su oso de peluche.
4. (engaged in)
This refers to an idiomatic word or phrase for which there is no word-for-word translation.
no direct translation
Since you're about it, will you make me some tea?Ya que estás en ello, ¿me preparas una taza de té?
While I'm about it, I'll ask our neighbor to watch the cat while we're away.De paso, le pediré a la vecina que nos cuide el gato mientras estamos fuera.
5. (in a place) (United Kingdom)
a. en
Lady Mary is walking about the park.Lady Mary está caminando en el parque.
b. por
We were strolling about the old quarter for a while and then went back to the hotel.Estuvimos paseando un rato por el casco antiguo y luego volvimos al hotel.
6. (on one's person) (United Kingdom)
a. con
I don't have the papers about me.No tengo los documentos conmigo.
An adverb is a word that describes a verb, an adjective, or other adverbs (e.g. to run quickly, very tired).
7. (approximately)
a. aproximadamente
There are about 40 guests in the hotel.Hay aproximadamente 40 huéspedes en el hotel.
b. alrededor de
The trout Alexander caught weighed about 55 pounds.La trucha que pescó Alexander pesaba alrededor de 55 libras.
c. más o menos
It was about 10 am when the doctor called.Eran más o menos las 10 am cuando llamó el doctor.
8. (on the point of; used with "to")
a. a punto de
The train is about to leave the station.El tren está a punto de salir de la estación.
9. (around; often used with "all")
a. por todas partes
There was candy all about after the Halloween party.Había dulces por todas partes después de la fiesta de Halloween.
b. de un lado a otro
The cat was running about like a madman all over the house.El gato corría de un lado a otro como un loco por toda la casa.
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