Quick answer
"De verdad" is an interjection which is often translated as "really", and "no" is an adverb which is often translated as "no". Learn more about the difference between "de verdad" and "no" below.
de verdad(
deh
 
behr
-
dahd
)
An interjection is a short utterance that expresses emotion, hesitation, or protest (e.g. Wow!).
1. (seriously)
a. really
¡Ganaste el premio mayor! - ¿De verdad?You won the grand prize! - Really?
An adjective is a word that describes a noun (e.g. the big dog).
2. (genuine)
a. real
¿Por qué me miras así? ¿Nunca has visto un vaquero de verdad?Why are you looking at me like that? Haven't you ever seen a real cowboy?
An adverb is a word that describes a verb, an adjective, or other adverbs (e.g. to run quickly, very tired).
3. (actually)
a. really
De verdad no sé si te guste lo que te traje, pero espero que sí.I really don't know if you'll like what I brought you, but I hope so.
4. (truly)
a. for real
Bien muchachos, estuvo bien la práctica, pero ahora juegan de verdad.Well boys, practice went well, but now it's time to play for real.
b. honestly
Cuando te conocí, de verdad no sabía que ibas a ser tan importante en mi vida.When I met you, I honestly didn't know how important you were going to be in my life.
c. really
Sí, de verdad me encanta el betabel crudo.Yes, I really do love raw beets.
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no(
noh
)
An adverb is a word that describes a verb, an adjective, or other adverbs (e.g. to run quickly, very tired).
1. (negation)
a. no
¿Te gustó el concierto? - No, ese estilo de música no me gusta.Did you like the concert? - No, I don't like that style of music.
b. not
No está lloviendo.It's not raining.
c. non-
Una organización no gubernamental es una asociación que actúa con independencia del gobierno.A non-governmental organization is an association that operates independently of government.
2. (in tag questions; asking confirmation)
a.
This refers to an idiomatic word or phrase for which there is no word-for-word translation.
no direct translation
Vamos a la fiesta esta noche ¿no?We're going to the party tonight, aren't we?
Firmaste el contrato ¿no?You signed the contract, didn't you?
3. (in tag questions; to make suggestions)
a.
This refers to an idiomatic word or phrase for which there is no word-for-word translation.
no direct translation
Te acompaño ¿no?I'll come with you, shall I?
Deberíamos llamarlos ¿no?We should call them, shouldn't we?
An interjection is a short utterance that expresses emotion, hesitation, or protest (e.g. Wow!).
4. (negation)
a. no
Quiero que limpies tu cuarto ahora mismo. - ¡No!I want you to clean your room right now. - No!
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