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QUICK ANSWER
"De" is a form of "de", a preposition which is often translated as "from". "De qué" is a phrase which is often translated as "what". Learn more about the difference between "de qué" and "de" below.
de qué(
deh
keh
)A phrase is a group of words commonly used together (e.g., once upon a time).
de(
deh
)A preposition is a word that indicates the relationship between a noun and another word (e.g., He ran through the door.).
a. no direct translation
This refers to an idiomatic word or phrase for which there is no word-for-word translation.
Te recojo en el coche de mi padre.I'll come get you in my father's car.
¿Esa no es la casa de Susana?Isn't that Susana's house?
a. no direct translation
This refers to an idiomatic word or phrase for which there is no word-for-word translation.
Voy a comprar otro traje de baño para el verano.I'm going to buy another bathing suit for the summer.
Se usa la palanca de cambios para cambiar las marchas.You use the gear shift to change the gears.
a. with
Me sorprendí llorando de pena al pensar en él.I caught myself crying with sorrow when I thought of him.
A feminine noun is almost always used with feminine articles and adjectives (e.g., la mujer bonita, la luna llena).
