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"Despite" is a preposition which is often translated as "a pesar de", and "although" is a conjunction which is often translated as "aunque". Learn more about the difference between "despite" and "although" below.
despite()
A preposition is a word that indicates the relationship between a noun and another word (e.g., He ran through the door.).
a. a pesar de
She was the one who paid the rent, despite having a much lower income.Era ella quien pagaba el alquiler, a pesar de tener unos ingresos mucho más bajos.
b. pese a
Obama signed sanctions against Venezuela despite threats from Maduro.Obama firmó sanciones contra Venezuela pese a las amenazas de Maduro.
although()
A conjunction is a word that connects words, phrases, clauses, or sentences (e.g., The cat and the dog slept.).