Carlos es ateo, pero jamás usaría palabras profanas cuando habla de tu religión.Carlos is an atheist, but he would never use irreverent words to talk about your religion.
Mi amigo es un profano pero siempre hace todo el ritual de la cata del vino como si fuera un experto.My friend is a layman but he always does the entire ritual of wine tasting as though he were an expert.
"Hay muchos profanos en este teatro que no entienden nada sobre ópera", se quejó Ágata."There are many laypeople in this theater who don't understand a thing about opera," complained Agata.
soy profano en la materiaI don't know anything about the subject;soy profano en músicaI don't know anything about music;I'm a layman when it comes to music