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Quick answer
"In spite of" is a preposition which is often translated as "a pesar de", and "despite" is a preposition which is also often translated as "a pesar de". Learn more about the difference between "in spite of" and "despite" below.
in spite of(
ihn
 
spayd
 
uhv
)
A preposition is a word that indicates the relationship between a noun and another word (e.g. He ran through the door.).
1. (despite)
a. a pesar de
We went to the baseball game in spite of the rain.Fuimos al partido de béisbol a pesar de la lluvia.
b. pese a
In spite of everything I still love her.Pese a todo la sigo queriendo.
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despite(
dih
-
spayt
)
A preposition is a word that indicates the relationship between a noun and another word (e.g. He ran through the door.).
1. (in spite of)
a. a pesar de
She was the one who paid the rent, despite having a much lower income.Era ella quien pagaba el alquiler, a pesar de tener unos ingresos mucho más bajos.
b. pese a
Obama signed sanctions against Venezuela despite threats from Maduro.Obama firmó sanciones contra Venezuela pese a las amenazas de Maduro.
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