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Quick answer
"En" is a preposition which is often translated as "in", and "centro" is a noun which is often translated as "center". Learn more about the difference between "en" and "centro" below.
en(
ehn
)
A preposition is a word that indicates the relationship between a noun and another word (e.g. He ran through the door.).
1. (indicating place)
a. in
Hay comida ya preparada en el supermercado.There's ready-made food in the supermarket.
b. on
Puedes poner los cubiertos en la mesa. You can put the silverware on the table.
2. (indicating time)
a. on
En 1969, aterrizamos en la luna.In 1969, we landed on the moon.
3. (indicating mode)
a. in
Si un oso te persigue, corre en zigzag.If a bear is chasing you, run in a zig-zag formation.
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centro(
sehn
-
troh
)
A masculine noun is used with masculine articles and adjectives (e.g. el hombre guapo, el sol amarillo).
1. (central point)
a. center
Regionalism used in the United States
(United States)
En el centro del mantel hay una estrella.There is a star in the center of the tablecloth.
b. centre (United Kingdom)
Pon un clavo de olor en el centro de la galleta.Put a clove in the centre of the biscuit.
c. middle
¡Tienen una máquina tragamonedas antigua justo en el centro de la sala!They've got an old slot machine right in the middle of their living-room!
2. (institution)
a. center
Regionalism used in the United States
(United States)
El centro juvenil está abierto después de la escuela.The youth center is open after school.
b. centre (United Kingdom)
Trabajo en un centro para mujeres golpeadas.I work at a centre for battered women.
3. (central area of a city)
a. center
Regionalism used in the United States
(United States)
¿Cómo puedo ir al centro de Chicago?How can I go to the center of Chicago?
b. centre (United Kingdom)
El centro está cerrado al tráfico.The centre is closed to traffic.
c. downtown
Regionalism used in the United States
(United States)
Ayer fui al centro al cine.Yesterday, I went downtown to the movies.
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