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QUICK ANSWER
"El" is a form of "el", a definite article which is often translated as "the". "Ellos" is a form of "ellos", a pronoun which is often translated as "they". Learn more about the difference between "el" and "ellos" below.
el(
ehl
)A definite article is a word that identifies a noun as specific or known to the speaker (e.g., the girl).
ellos(
eh
-
yohs
)A pronoun is a word that stands in for a noun (e.g., she).
b. them (after prepositions)
Si confías en ellos, dales las llaves.If you trust them, give them the keys.
c. them (in comparisons)
Mi hermano y yo somos tan altos como ellos.My brother and I are as tall as them.