Quick answer
"Come on" is an interjection which is often translated as "vamos", and "let's go" is a phrase which is often translated as "vámonos". Learn more about the difference between "come on" and "let's go" below.
come on(
kuhm
 
an
)
An interjection is a short utterance that expresses emotion, hesitation, or protest (e.g. Wow!).
1. (used to encourage)
a. vamos
Come on! We can still win the game!¡Vamos! ¡Aún podemos ganar el partido!
b. ándale
Regionalism used in Mexico
(Mexico)
Come on! Hit the piñata harder!¡Ándale! ¡Dale más fuerte a la piñata!
c. dale (River Plate)
Come on! Get dressed, or we'll be late.Dale! Vístete o llegaremos tarde.
d. venga
Come on! You can do it!¡Venga! ¡Sí se puede!
An intransitive verb phrase is a phrase that combines a verb with a preposition or other particle and does not require a direct object (e.g. Everybody please stand up.).
intransitive verb phrase
2. (to begin)
a. empezar
I heard thunder. I think a storm is coming on.He oído truenos. Creo que está empezando una tempestad.
3. (theater)
a. salir a escena
After they finish the song, you come on and do your comedy routine.Después de la canción, tú sales a escena y haces tu número de comedia.
4. (to turn on)
a. encenderse
We were asleep when the TV suddenly came on.Estábamos dormidos cuando de repente se encendió la tele.
5. (to behave)
a. dar la impresión de ser
He came on all sweet, but he turned out to be a jerk.Dio la impresión de ser amable, pero resultó ser un patán.
b. fingir ser
The salesman came on really nice, but he just wanted our money.El dependiente fingía ser muy simpático, pero solo quería nuestro dinero.
6. (to progress)
a. avanzar
The violin parts for the concert are coming on quite nicely.Las partituras de violín para el concierto están avanzando bastante bien.
7.
A word or phrase that is commonly used in conversational speech (e.g. skinny, grandma).
(colloquial)
(to flirt)
a. coquetear
I'm not sure if the guy at the bar is just friendly or if he's coming on to me.No estoy seguro si el chico en la barra está amable nomás o si está coqueteando conmigo.
b. echar los perros
I was eating dinner by myself, when a beautiful woman started coming on to me.Cenaba allí solo cuando una mujer hermosa empezó a echarme los perros.
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let's go(
lehts
 
go
)
A phrase is a group of words commonly used together (e.g once upon a time).
phrase
1. (general)
a. vámonos
We are late. Just grab your purse and let's go.Vamos a llegar tarde. Toma tu bolso y vámonos.
b. vamos
Let's go out for dinner to celebrate our anniversary.Vamos a cenar fuera para celebrar nuestro aniversario.
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