Possible Results:
qué materia no toma este semestre
-what subject he's not taking this semester
¿Qué materia no toma este semestre?
-What subject isn't he taking this semester?

qué materia no toma este semestre

A phrase is a group of words commonly used together (e.g., once upon a time).
phrase
a. what subject he's not taking this semester (masculine)
Me pregunto qué materia no toma este semestre. - ¿Historia quizá? Dijo que no le gustaba.I wonder what subject he's not taking this semester. - History maybe? He said he didn't like it.
b. what subject she's not taking this semester (feminine)
No recuerdo qué materia no toma este semestre. - Pregúntale a ella.I can't remember what subject she's not taking this semester. - Ask her.
2.
A word or phrase used to refer to the second person formal “usted” by their conjugation or implied context (e.g., usted).
(formal)
(second person singular)
a. what subject you're not taking this semester
Dígame qué materia no toma este semestre y por qué.Tell me what subject you're not taking this semester and why.
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