paciente cero

el paciente cero, la paciente cero
This means that the noun can be masculine or feminine, depending on the gender of the noun it refers to (e.g., el doctor, la doctora).
masculine or feminine noun
a. patient zero
El paciente cero de Madrid acababa de regresar de un viaje por el norte de Italia y allí pudo contraer el coronavirus.Madrid's patient zero had just returned from a trip through northern Italy, where he may have caught the coronavirus.
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