Usage note
This word may also be spelled "cusco" or "Cusco."
proper noun
1. (city) 
a. Cusco 
Dicen que Cusco, o Cuzco, es la ciudad más bella del Perú.They say Cusco, or Cuzco, is the most beautiful city in Peru.
masculine noun
2. (colloquial) (dog) (River Plate) 
a. mongrel 
¿De qué raza es tu perro? - Es solo un cuzco.What breed is your dog? - It's just a mongrel.
b. mutt 
La anciana paseaba a su cuzco sin correa.The old lady would walk her mutt without a leash.
3. (acting like a grown-up) (River Plate) 
a. no direct translation 
Es un poco cuzca, de acuerdo, pero la niña sabe lo que dice.She speaks like an adult, that's true, but the girl makes a lot of sense.
Este niño tan cuzco me pone frenético.This pretentious brat makes me mad.
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