despite all the ups and downs

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Vipassana teaches you to be aware and equanimous, that is, balanced, despite all the ups and downs of life.
La Vipassana te enseña a ser consciente y ecuánime, es decir, equilibrado, a pesar de todos los altibajos de la vida.
Despite all the ups and downs, things turned out for the best.
A pesar de todos los altibajos, las cosas se resolvieron para mejor.
Despite all the ups and downs, Alexander consistently adhered to the private character of the family business.
A pesar de todos los altibajos, Alexander defendió permanentemente el carácter privado del negocio familiar.
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