What's wrong with Margarita?

What's wrong with Margarita? - She has a really bad headache.
¿Qué tiene Margarita? - Le duele mucho la cabeza.
Andrea, what's wrong with Margarita? She looks sad.
Andrea, ¿qué tiene Margarita? Se ve triste.
I'd like to know what's wrong with Margarita. I'd like to be able to help her.
Me gustaría saber qué tiene Margarita. Quisiera poder ayudarla.
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