QUICK ANSWER
"Yo" is a pronoun which is often translated as "I", and "mis amigas" is a phrase which is often translated as "my friends". Learn more about the difference between "yo" and "mis amigas" below.
yo(
yoh
)A pronoun is a word that stands in for a noun (e.g., she).
A masculine noun is used with masculine articles and adjectives (e.g., el hombre guapo, el sol amarillo).
3. (psychology)
mis amigas(
mees
ah
-
mee
-
gahs
)A phrase is a group of words commonly used together (e.g., once upon a time).
a. my friends
Me voy de vacaciones con mis amigas Jimena y Lucía.I'm going on vacation with my friends Jimena and Lucia.
b. my female friends (feminine)
A word or phrase that is feminine (e.g., la manzana).
Tanto mis amigas como mis amigos ocupan puestos de mucha responsabilidad.Both my female and male friends are in positions that involve a great deal of responsibility.