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QUICK ANSWER
"What is it" is a form of "what is it", a phrase which is often translated as "qué es". "Yes" is an interjection which is often translated as "sí". Learn more about the difference between "yes" and "what is it" below.
yes(
yehs
)An adverb is a word that describes a verb, an adjective, or other adverbs (e.g., to run quickly, very tired).
An interjection is a short utterance that expresses emotion, hesitation, or protest (e.g., Wow!).
A noun is a word referring to a person, animal, place, thing, feeling, or idea (e.g., man, dog, house).
what is it
A phrase is a group of words commonly used together (e.g., once upon a time).
1. (general)
c. no direct translation
This refers to an idiomatic word or phrase for which there is no word-for-word translation.
I can tell that you're trying to hold back your tears. What is it, sweetheart?Me doy cuenta de que estás intentando contener las lágrimas. ¿Qué pasa, cariña?
You bought a new house? What is it like?¿Compraste una casa nueva? ¿Cómo es?