Quick answer
"Whose" is a pronoun which is often translated as "de quién", and "who's" is a phrase which is often translated as "quién es". Learn more about the difference between "whose" and "who's" below.
A pronoun is a word that stands in for a noun (e.g. she).
1. (possessive)
a. de quién
Whose are these DVDs?¿De quién son estos DVDs?
An adjective is a word that describes a noun (e.g. the big dog).
2. (possessive)
a. de quién
I don't know whose car it is.No sé de quién es el coche.
b. cuyo
That's the girl whose boyfriend was sent to jail.Esa es la chica cuyo novio fue enviado a la cárcel.
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A phrase is a group of words commonly used together (e.g once upon a time).
1. (in questions)
a. quién es
Who's the man who's sitting next to you? - My cousin.¿Quién es el hombre que está sentado a tu lado? - Mi primo.
b. quién está
Who's there? - It's me, Susan.¿Quién está ahí? - Soy yo, Susan.
2. (in statements)
a. que es
Mark had an affair with the woman who's now our boss.Mark tuvo un romance con la mujer que es ahora nuestra jefa.
b. que está
The girl who's now talking to Sarah is my new girlfriend.La chica que está hablando ahora con Sarah es mi nueva novia.
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