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Quick answer
"Uy" is an interjection which is often translated as "oh", and "lo siento" is a phrase which is often translated as "I'm sorry". Learn more about the difference between "uy" and "lo siento" below.
An interjection is a short utterance that expresses emotion, hesitation, or protest (e.g. Wow!).
1. (surprised)
a. oh
¡Uy! Me asustaste.Oh! You startled me.
b. wow
¡Uy! Qué majestuosas son estas montañas.Wow! These mountains are so majestic.
2. (caused by pain)
a. ow
¡Uy! Me dolió mucho esa inyección.Ow! That shot really hurt.
b. ouch
¡Uy! Me quemé en la estufa.Ouch! I burned myself on the stove.
3. (disgust)
a. ew
¡Uy! ¡No me enseñes tus mocos!Ew! Don't show me your boogers!
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lo siento(
A phrase is a group of words commonly used together (e.g once upon a time).
1. (expressing regret)
a. I'm sorry
Rompí tu ordenador. Lo siento.I broke your computer. I'm sorry.
2. (expressing condolences)
a. I'm sorry
Me enteré del fallecimiento de tu padre. Lo siento.I heard about the death of your father. I'm sorry.
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