vs 

QUICK ANSWER
"Una vez más" is a phrase which is often translated as "once again", and "de nuevo" is a phrase which is often translated as "again". Learn more about the difference between "una vez más" and "de nuevo" below.
una vez más(
oo
-
nah
 
behs
 
mahs
)
A phrase is a group of words commonly used together (e.g., once upon a time).
phrase
a. once again
Aquí estamos, una vez más, enfrentados a una crisis económica provocada por el manejo ineficiente de la economía.Here we are, once again, facing an economic crises caused by an inefficient management of the economy.
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de nuevo(
deh
 
nweh
-
boh
)
A phrase is a group of words commonly used together (e.g., once upon a time).
phrase
a. again
Nos paramos un rato para descansar y después partimos de nuevo.We stopped to rest for a while, and then we set off again.
b. once again
Has cocinado una cena deliciosa de nuevo, mi amor.Once again, you've cooked a delicious dinner, my dear.
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