Quick answer
"On the weekend" is an adverb which is often translated as "el fin de semana", and "at weekends" is a phrase which is often translated as "los fines de semana". Learn more about the difference between "on the weekend" and "at weekends" below.
on the weekend(
An adverb is a word that describes a verb, an adjective, or other adverbs (e.g. to run quickly, very tired).
1. (general)
a. el fin de semana
I get up early during the week, but on the weekend I sleep in.Me levanto temprano durante la semana, pero el fin de semana duermo hasta tarde.
b. durante el fin de semana
On the weekend, I like to work in my garden.Me gusta trabajar en mi jardín durante el fin de semana.
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at weekends
A phrase is a group of words commonly used together (e.g once upon a time).
1. (general) (United Kingdom)
a. los fines de semana
I usually see my friends at weekends.Usualmente veo a mis amigos los fines de semana.
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