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"Most likely" is a form of "most likely", an adjective which is often translated as "más probable". "No one knows" is a phrase which is often translated as "nadie sabe". Learn more about the difference between "most likely" and "no one knows" below.
most likely(
most
 
layk
-
li
)
An adjective is a word that describes a noun (e.g., the big dog).
adjective
a. más probable
I think that's the most likely outcome.Creo que ese es el resultado más probable.
b. con más probabilidades
Lisa is the most likely teacher to win the principal's award.Lisa es la maestra con más probabilidades de ganar el premio que otorgará la directora.
An adverb is a word that describes a verb, an adjective, or other adverbs (e.g., to run quickly, very tired).
adverb
a. muy probablemente
You will most likely have to wait an hour in line.Muy probablemente tendrá que esperar una hora en fila.
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no one knows(
no
 
wuhn
 
noz
)
A phrase is a group of words commonly used together (e.g., once upon a time).
phrase
a. nadie sabe
No one know when the power will return.Nadie sabe cuando volverá la luz.
b. no se sabe
No one knows how much damage the oncoming hurricane might do.No se sabe cuánto daño podría causar el huracán que se aproxima.
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