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"It's" is a form of "it's", a contraction which is often translated as "es". "Yes" is an interjection which is often translated as "sí". Learn more about the difference between "it's" and "yes" below.
it's(
ihts
)A contraction is a shortened form of a word or group of words made by omitting a sound or letter (e.g., don't).
yes(
yehs
)An adverb is a word that describes a verb, an adjective, or other adverbs (e.g., to run quickly, very tired).
An interjection is a short utterance that expresses emotion, hesitation, or protest (e.g., Wow!).
A noun is a word referring to a person, animal, place, thing, feeling, or idea (e.g., man, dog, house).
