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QUICK ANSWER
"How come" is a form of "how come", an adverb which is often translated as "cómo es que". "Who knows" is a phrase which is often translated as "quién sabe". Learn more about the difference between "how come" and "who knows" below.
how come(
hau
kuhm
)An adverb is a word that describes a verb, an adjective, or other adverbs (e.g., to run quickly, very tired).
1. (colloquial) (general)
A word or phrase that is commonly used in conversational speech (e.g., skinny, grandma).
who knows(
hu
noz
)A phrase is a group of words commonly used together (e.g., once upon a time).
1. (general)
a. quién sabe
Is this food for everybody? - Who knows? But I'm going to eat it.¿Esta comida es para todos? - ¿Quién sabe? Pero yo la voy a comer.
