vs
QUICK ANSWER
"Excuse me" is a phrase which is often translated as "perdón", and "Can you repeat that?" is a phrase which is often translated as "¿Puedes repetirlo?". Learn more about the difference between "excuse me" and "Can you repeat that?" below.
excuse me( 
ehk
-
skyuz
mi
)A phrase is a group of words commonly used together (e.g., once upon a time).
Can you repeat that?(   
kahn
yu
ruh
-
pit
thaht
)A phrase is a group of words commonly used together (e.g., once upon a time).
1. (general)
a. ¿Puedes repetirlo?  (informal)
A word or phrase used to refer to the second person informal “tú” by their conjugation or implied context (e.g., How are you?).
Can you repeat that? I didn't catch the end.¿Puedes repetirlo? No pesqué la última parte.
b. ¿Puede repetirlo?  (formal)
A word or phrase used to refer to the second person formal “usted” by their conjugation or implied context (e.g., usted).
Can you repeat that? Someone was talking and I didn't quite hear.¿Puede repetirlo? Alguien hablaba y no conseguí oírlo.