Quick answer
"De qué" is a phrase which is often translated as "what", and "cual" is a pronoun which is often translated as "which". Learn more about the difference between "de qué" and "cual" below.
de qué(
deh
 
keh
)
A phrase is a group of words commonly used together (e.g once upon a time).
phrase
1. (interrogative)
a. what
Necesito saber de qué se trata.I need to know what it's about.
¿De qué estás hablando?What are you talking about?
b. which
Platicaron acerca de qué escuela iban a elegir para su hija.They talked about which school they would choose for their daughter.
c. from which
¿De qué país eres?Which country are you from?
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cual(
kwahl
)
A pronoun is a word that stands in for a noun (e.g. she).
1. (relative)
a. which (thing)
El hotel en el cual pasé mis vacaciones de verano ha cerrado.The hotel in which I spent my summer holiday has been closed.
b. who (person)
Mi hermano, el cual trabaja en un restaurante, encontró esto en el suelo el otro día.My brother, who works in a restaurant, found this on the floor the other day.
An adverb is a word that describes a verb, an adjective, or other adverbs (e.g. to run quickly, very tired).
2. (like)
a. as
Ella es bella cual flor.She is as beautiful as a flower.
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