"De nada" is a phrase which is often translated as "you are welcome", and "por supuesto" is a phrase which is often translated as "of course". Learn more about the difference between "de nada" and "por supuesto" below.
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A phrase is a group of words commonly used together (e.g once upon a time).
1. (expressing courtesy)
a. you are welcome
¡Gracias por las flores! - De nada, espero que te gusten.Thanks for the flowers! - You are welcome. I hope you like them.
b. you're welcome
¡Gracias por el regalo! - De nada.Thanks for the gift! - You're welcome.
c. it's nothing
Muchas gracias por dejarme quedar contigo. - De nada.Thank you for letting me stay with you. - It's nothing.