Quick answer
"De nada" is a phrase which is often translated as "you are welcome", and "de todo" is an adverb which is often translated as "a little bit of everything". Learn more about the difference between "de nada" and "de todo" below.
de nada(
deh
 
nah
-
dah
)
A phrase is a group of words commonly used together (e.g once upon a time).
phrase
1. (expressing courtesy)
a. you are welcome
¡Gracias por las flores! - De nada, espero que te gusten.Thanks for the flowers! - You are welcome. I hope you like them.
b. you're welcome
¡Gracias por el regalo! - De nada.Thanks for the gift! - You're welcome.
c. it's nothing
Muchas gracias por dejarme quedar contigo. - De nada.Thank you for letting me stay with you. - It's nothing.
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de todo(
deh
 
toh
-
doh
)
An adverb is a word that describes a verb, an adjective, or other adverbs (e.g. to run quickly, very tired).
1. (used to refer to an assortment of things)
a. a little bit of everything
Compré de todo: cerveza, vino, ginebra, ron y vodka.I bought a little bit of everything: beer, wine, gin, rum, and vodka.
A phrase is a group of words commonly used together (e.g once upon a time).
phrase
2. (of everything)
a. of all
¿Qué piensa tu padre de todo esto?What does your father think of all this?
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