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QUICK ANSWER
"De donde eres" is a form of "de donde eres", a phrase which is often translated as "where you're from". "Quién eres tú" is a form of "quién eres tú", a phrase which is often translated as "who you are". Learn more about the difference between "de donde eres" and "quién eres tú" below.
de donde eres(
deh
dohn
-
deh
eh
-
rehs
)A phrase is a group of words commonly used together (e.g., once upon a time).
1. (informal) (second person singular)
A word or phrase used to refer to the second person informal “tú” by their conjugation or implied context (e.g., How are you?).
a. where you're from
¿Y cómo es el lugar de donde eres en África?So how's the place where you're from in Africa?
b. where you are from
¿Es la ciudad de donde eres la capital del país?Is the city where you are from the capital of your country?
d. you come from
Jamaica, la isla de donde eres, es un lugar bellísimo.Jamaica, the island you come from, is a really beautiful place.
quién eres tú(
kyehn
eh
-
rehs
too
)A phrase is a group of words commonly used together (e.g., once upon a time).
a. who you are
¿Ves ese chico tan lindo? Acaba de preguntarme que quién eres tú.See that cute boy? He just asked me who you are.
a. who are you
¿Quién eres tú para criticarme si no me conoces?Who are you to criticize me if you don't know me?