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QUICK ANSWER
"Cuáles" is a form of "cuál", a pronoun which is often translated as "which". "Con quienes" is a form of "con quienes", a phrase which is often translated as "who ... with". Learn more about the difference between "cuáles" and "con quienes" below.
cuál(
kwahl
)A pronoun is a word that stands in for a noun (e.g., she).
a. which (among a group of options)
¿Cuál de estas camisas me queda mejor?Which of these shirts suits me best?
b. which one (among a group of options)
No sé cuál quiere.I don't know which one she wants.
¿Cuál es mejor?Which one is better?
An adjective is a word that describes a noun (e.g., the big dog).
a. which (among a group of options)
¿Cuál color iría mejor en el salón?Which color would look best in the living room?
con quienes(
kohn
kyeh
-
nehs
)A phrase is a group of words commonly used together (e.g., once upon a time).
a. who ... with
Mis suegros, con quienes me llevo muy bien, me ayudan mucho con los niños.My parents in-law, who I get along very well with, help me a lot with the kids.
c. no direct translation
This refers to an idiomatic word or phrase for which there is no word-for-word translation.
¿Las personas con quienes estabas ayer son tus compañeros de trabajo?Are the people you were with yesterday your coworkers?
Los hombres con quienes me casé eran todos guapos e inteligentes.The men I married were all handsome and smart.
