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What is ¿Cómo es tu profesor de español?" In English
2 Answers
When the machine translator gives three nearly identical answers, you can have a fair amount of confidence it is correct (and in this case I will add my assurance):
http://www.spanishdict.com/translate/¿Cómo es tu profesor de español
Do keep in mind the "how is" in this case, since you are using ser, refers to what is the professor like, his characteristics, probably how is he as a teacher. If you were asking about the health of the person, the condition, you would use estar.
I believe that ¿Cómo es tu professor de español? translates to, "How is your Spanish teacher?"