What is the meaning of?

Question

it sets my teeth on ledge when you bite nails...

Answer 1

mad enough to chew nails (and spit rivets) and angry enough to chew nails; mad enough to spit nails Inf. Fig. very angry, as if to be able to bite through metal nails. I am mad enough to chew nails! Who took my checkbook? Her sudden tirade made him angry enough to chew nails. He stomped in, mad enough to chew nails and spit rivets.

These are just a few of the many American expressions we have about biting a nail. "I'm so mad I can bite a nail in half" is the one I remember.

Here are a few more that will give you a laugh:

That’s about as useful as a trap door on a canoe! You look about as happy as a tick on a fat dog.
That boy’s more slippery than snot on a glass doorknob. Why don’t you just take a long walk off a short pier. They’re off like a herd of turtles. She’s resting in peace in the marble orchard.

Answer 2

Welcome to the forum!

If something "sets my teeth on edge", it bothers me a lot, often without a good reason.

"to have teeth set on edge" = "estar fastidiado/picado/molesto/enfadado"?