¿Cuál es su destino de viaje favorito?
Para mí es España y Portugal
10 Answers
Is there a good rule to know when to use Cuál instead of Que, or are they interchangeable?
The usual (but not infallible) rule would be "Use 'que' when you want a definition of whatever follows es/son and use 'cuál' when you are asking for an example/instance of whatever follows. An alternative (for English speakers) would be if you can reasonably replace "what" by "which" in your question, then you should be using 'cuál'.
A mi cama..
Mi destino de viaje favorito es Virginia y Maine. Tengo que irme a México, España y ninguno país en Sudamérica tarde o temprano. 
Para mi es Madrid, España. Porque es una cuidad muy bonita y interesante.
Me encanta Oaxaca, Mexico
Beul nan Uamh, an Island to the west of Scotland (means mouth of the grave-actually cavern but here it means grave).
Para mi es Baja California, Mexico.
Also, if I were to write your title-question myself, I would have made the mistake of writing, "Que es su destino de viaje favorito" - Is there a good rule to know when to use Cuál instead of Que, or are they interchangeable?
Ups, I put this question in the wrong section. Is there some way to move this to the travel section?
Punta Cana es la mia. 
para mi, las islas Seychelles
